RelatedData1.3 Cluster 2 markers identified in single-nucleus RNA-seq analysis of P. tepidariorum embryos at late stage 5
Gene ID (NCBI) p_val avg_log2FC *pct.1 *pct.2 p_val_adj Gene ID (NCBI) Product (NCBI) aug3 gene model Expression in RNAi embryos**
LOC107456035 0.00E+00 1.95217979 0.947 0.326 0.00E+00 LOC107456035 homeobox protein B-H1 aug3.g8250 hh5 - ptc5 +   msx6 +      
LOC107436847 9.93E-305 2.11076696 0.904 0.318 2.02E-300 LOC107436847 T-box transcription factor TBX20-like aug3.g11865 hh5 - ptc5 +          
LOC107437002 1.79E-284 1.66642275 0.992 0.677 3.63E-280 LOC107437002 adhesion G protein-coupled receptor L1 aug3.g9493 hh5 - ptc5 +          
LOC107437305 4.08E-197 1.56292624 0.862 0.394 8.30E-193 LOC107437305 zinc finger protein ZIC 4-like aug3.g12202 hh5 - ptc5 +          
LOC107455686 2.71E-175 1.34554772 0.566 0.144 5.51E-171 LOC107455686 homeobox protein Hox-A1-like aug3.g7954 hh5 - ptc5 +          
LOC107451579 6.54E-126 1.18101037 0.844 0.5 1.33E-121 LOC107451579 E3 ubiquitin-protein ligase Rnf220 aug3.g4121 hh5 - ptc5 -          
LOC107440240 1.39E-113 0.9932993 0.754 0.423 2.83E-109 LOC107440240 protein patched-like aug3.g14374 hh5 -            
LOC107436350 8.87E-113 0.82327694 0.983 0.813 1.80E-108 LOC107436350 glypican-6 aug3.g11833,aug3.g11486 hh5 - ptc5 +          
LOC107442769 5.55E-110 0.76082486 0.996 0.897 1.13E-105 LOC107442769 neurogenic locus Notch protein aug3.g27737,aug3.g21218              
LOC107455688 2.13E-109 1.07020055 0.488 0.161 4.32E-105 LOC107455688 uncharacterized LOC107455688 　 　 　 　 　 　 　 　
LOC107449282 6.59E-108 0.62445261 1 0.99 1.34E-103 LOC107449282 uncharacterized LOC107449282 aug3.g20669 hh5 - ptc5 +          
LOC107436358 1.10E-106 0.73065703 0.99 0.82 2.24E-102 LOC107436358 fasciclin-2 aug3.g11491              
LOC107456793 2.22E-105 0.94146564 0.298 0.057 4.51E-101 LOC107456793 T-box transcription factor TBX20 aug3.g8837 hh5 - ptc5 +          
LOC107446842 1.27E-88 0.67754898 0.972 0.799 2.57E-84 LOC107446842 uncharacterized LOC107446842 aug3.g1487,aug3.g1486 hh5 - ptc5 -       fuchi3 +  
LOC107443668 3.65E-88 0.93156989 0.435 0.15 7.41E-84 LOC107443668 metalloprotease TIKI2 aug3.g17382,aug3.g18676              
LOC107457539 2.51E-82 0.79249956 0.879 0.611 5.10E-78 LOC107457539 zinc finger homeobox protein 3 aug3.g11268 hh5 -         fuchi3 +  
LOC107453771 5.63E-81 0.99882106 0.514 0.219 1.14E-76 LOC107453771 SPARC-related modular calcium-binding protein 2 aug3.g5781 hh5 - ptc5 -          
LOC107440157 3.15E-80 0.84804497 0.78 0.44 6.40E-76 LOC107440157 zinc finger protein 423 aug3.g14296 hh5 - ptc5 +          
LOC107453597 4.97E-77 0.80815779 0.93 0.703 1.01E-72 LOC107453597 fibroblast growth factor 8 aug3.g5611 hh5 - ptc5 +          
LOC107436125 3.85E-55 0.45131231 0.225 0.06 7.83E-51 LOC107436125 protein gooseberry aug3.g11337 hh5 - ptc5 +         fuchi5 -
LOC107456830 6.67E-55 0.65332719 0.847 0.625 1.36E-50 LOC107456830 serine-rich adhesin for platelets aug3.g8856 hh5 - ptc5 +          
LOC107443696 3.18E-54 0.7982734 0.453 0.22 6.46E-50 LOC107443696 protein snail homolog Sna aug3.g416,aug3.g417 hh5 - ptc5 +          
LOC107451394 3.31E-52 0.69381163 0.486 0.241 6.73E-48 LOC107451394 frizzled-5 aug3.g4009 hh5 -            
LOC107450063 1.75E-49 0.56519547 0.877 0.674 3.56E-45 LOC107450063 homeobox protein Meis1 aug3.g3111 hh5 -            
LOC107437748 4.49E-49 0.4681459 0.813 0.561 9.13E-45 LOC107437748 adipolin aug3.g12543 hh5 - ptc5 +          
LOC107450690 2.21E-48 0.59669461 0.769 0.548 4.49E-44 LOC107450690 uncharacterized LOC107450690 aug3.g25707 hh5 + ptc5 +          
LOC107449667 3.80E-46 0.69377147 0.457 0.234 7.73E-42 LOC107449667 centromere-associated protein E aug3.g10461 hh5 - ptc5 +       fuchi3 -  
LOC122270466 7.58E-43 0.29368565 0.125 0.023 1.54E-38 LOC122270466 uncharacterized LOC122270466 aug3.g12205,aug3.g12204              
LOC107457189 3.40E-42 0.43189578 0.502 0.251 6.91E-38 LOC107457189 homeobox protein OTX2-A-like aug3.g9172 hh5 - ptc5 +          
LOC107450101 4.21E-41 0.3575733 0.206 0.064 8.56E-37 LOC107450101 dendritic arbor reduction protein 1 aug3.g15550 hh5 -            
LOC107439560 9.94E-39 0.49591191 0.512 0.294 2.02E-34 LOC107439560 homeobox protein Meis2 aug3.g13867,aug3.g13868 hh5 - ptc5 +          
LOC107454167 7.85E-38 0.31008562 0.721 0.454 1.60E-33 LOC107454167 dorsal-ventral patterning protein Sog-like aug3.g23966   ptc5 -       fuchi3 +  
LOC107444058 1.72E-34 0.57305299 0.293 0.133 3.49E-30 LOC107444058 putative sodium-dependent multivitamin transporter aug3.g7417              
LOC107442231 2.96E-34 0.44235916 0.761 0.602 6.01E-30 LOC107442231 uncharacterized LOC107442231 aug3.g27564,aug3.g20669,aug3.g20671              
LOC107441084 1.13E-32 0.52887088 0.714 0.545 2.30E-28 LOC107441084 low-density lipoprotein receptor-related protein 2 aug3.g9796           fuchi3 +  
LOC107439046 4.75E-32 0.43379959 0.362 0.187 9.66E-28 LOC107439046 homeobox protein extradenticle aug3.g13538,aug3.g27748,aug3.g27747 hh5 -            
LOC107445501 5.71E-32 0.41452974 0.948 0.867 1.16E-27 LOC107445501 transducin-like enhancer protein 4 aug3.g25605,aug3.g25606 hh5 -            
LOC107456864 5.22E-31 0.41495531 0.925 0.811 1.06E-26 LOC107456864 exonuclease GOR-like aug3.g18504,aug3.g1256              
LOC107450100 6.95E-31 0.29754589 0.585 0.349 1.41E-26 LOC107450100 homeobox protein DLX-6-like aug3.g15531   ptc5 -          
LOC107454846 3.24E-30 0.51707639 0.753 0.591 6.59E-26 LOC107454846 RNA-binding protein fusilli aug3.g10830 hh5 - ptc5 +          
LOC107444748 2.35E-28 0.49013897 0.672 0.494 4.78E-24 LOC107444748 uncharacterized LOC107444748 aug3.g18068 hh5 -            
LOC107438554 6.48E-28 0.29761705 0.154 0.052 1.32E-23 LOC107438554 muscleblind-like protein 2 aug3.g13179,aug3.g5153 hh5 -            
LOC107436691 1.50E-27 0.36064529 0.881 0.675 3.04E-23 LOC107436691 uncharacterized LOC107436691 aug3.g11765 hh5 - ptc5 -          
LOC107447205 3.57E-25 0.49389033 0.629 0.467 7.26E-21 LOC107447205 roundabout homolog 1 aug3.g1658              
LOC107445694 2.99E-22 0.32202071 0.929 0.821 6.07E-18 LOC107445694 unconventional myosin-Vb aug3.g9254,aug3.g6148,aug3.g21618              
LOC107449611 5.81E-22 0.30234453 0.927 0.783 1.18E-17 LOC107449611 protein dachsous aug3.g2859 hh5 -            
LOC107454275 6.04E-21 0.33774548 0.153 0.061 1.23E-16 LOC107454275 transcription factor SOX-4-like aug3.g24008,aug3.g16006              
LOC107438242 1.09E-19 0.35634925 0.836 0.73 2.22E-15 LOC107438242 growth arrest-specific protein 2 aug3.g12936 hh5 +            
LOC107438758 1.63E-19 0.25605849 0.942 0.877 3.31E-15 LOC107438758 epidermal growth factor receptor aug3.g13345,aug3.g13344              
LOC122271530 9.05E-19 0.41270004 0.307 0.183 1.84E-14 LOC122271530 protein yippee-like 1 aug3.g11843,aug3.g11842   ptc5 +          
LOC107439303 3.07E-18 0.27829704 0.632 0.476 6.23E-14 LOC107439303 hemicentin-2 aug3.g13686              
LOC107453655 6.32E-18 0.26648708 0.971 0.894 1.28E-13 LOC107453655 RNA-binding protein MEX3B aug3.g5665              
LOC107456312 1.64E-16 0.33111885 0.618 0.475 3.33E-12 LOC107456312 smoothened homolog aug3.g8490   ptc5 +          
LOC107450601 6.33E-16 0.30796125 0.842 0.773 1.29E-11 LOC107450601 uncharacterized LOC107450601 aug3.g3466,aug3.g3467,aug3.g25011              
LOC107451335 3.32E-15 0.27367225 0.549 0.402 6.75E-11 LOC107451335 fatty acid-binding protein aug3.g3973              
LOC107450096 1.03E-14 0.3504225 0.546 0.423 2.09E-10 LOC107450096 sodium- and chloride-dependent glycine transporter 1 aug3.g15542 hh5 +            
LOC107445081 4.72E-13 0.33756602 0.393 0.279 9.58E-09 LOC107445081 SEC14-like protein 2 aug3.g18290   ptc5 +          
LOC107453499 8.84E-13 0.37239401 0.431 0.312 1.80E-08 LOC107453499 zinc finger homeobox protein 4 aug3.g25763             fuchi5 +
LOC107445214 9.15E-13 0.31269103 0.317 0.21 1.86E-08 LOC107445214 sodium-dependent neutral amino acid transporter B(0)AT3 aug3.g18382,aug3.g18383              
LOC107454759 2.00E-12 0.26908189 0.269 0.172 4.07E-08 LOC107454759 LARGE xylosyl- and glucuronyltransferase 1 aug3.g24112              
LOC107445477 2.57E-11 0.26645887 0.564 0.449 5.22E-07 LOC107445477 inaD-like protein aug3.g25607   ptc5 +          
LOC107440894 6.15E-11 0.28603816 0.434 0.325 1.25E-06 LOC107440894 latrophilin Cirl aug3.g56              
LOC107457269 8.23E-11 0.310273 0.354 0.256 1.67E-06 LOC107457269 uncharacterized LOC107457269 aug3.g16370              
LOC107446210 9.24E-11 0.3108749 0.57 0.458 1.88E-06 LOC107446210 zinc transporter ZIP6 aug3.g1267           fuchi3 +  
LOC107443484 1.82E-10 0.28949893 0.352 0.259 3.69E-06 LOC107443484 nostrin aug3.g27986 hh5 +            
LOC107456361 3.41E-10 0.32208176 0.487 0.384 6.92E-06 LOC107456361 uncharacterized LOC107456361 aug3.g10951              
LOC107438376 8.13E-10 0.25472831 0.524 0.42 1.65E-05 LOC107438376 cadherin-87A aug3.g13039              
LOC107456350 2.15E-09 0.25080602 0.255 0.172 4.36E-05 LOC107456350 retinol dehydrogenase 7 aug3.g8507              
LOC107445773 1.01E-08 0.25354107 0.465 0.373 2.05E-04 LOC107445773 single-stranded DNA-binding protein 3 aug3.g1165              
LOC107456288 1.57E-08 0.25728429 0.44 0.35 3.20E-04 LOC107456288 isocitrate dehydrogenase [NADP] cytoplasmic aug3.g8458              
LOC107455149 1.62E-07 0.25094968 0.433 0.353 3.28E-03 LOC107455149 DNA repair protein RAD50-like aug3.g6866,aug3.g6867   ptc5 +   msx6 +      
LOC107447950 3.43E-07 0.25590008 0.333 0.254 6.97E-03 LOC107447950 protein lifeguard 2 aug3.g15222,aug3.g6216 hh5 +            
LOC107449498 3.53E-06 0.25388216 0.385 0.311 7.17E-02 LOC107449498 serine proteinase stubble aug3.g15440