RelatedData1.4 Cluster 3 markers identified in single-nucleus RNA-seq analysis of P. tepidariorum embryos at late stage 5
Gene ID (NCBI) p_val avg_log2FC *pct.1 *pct.2 p_val_adj Gene ID (NCBI) Product (NCBI) aug3 gene model Expression in RNAi embryos**
LOC107438641 0.00E+00 3.16774318 0.895 0.152 0.00E+00 LOC107438641 transcription factor Sox-13 aug3.g13250              
LOC107451809 0.00E+00 3.7880538 0.979 0.206 0.00E+00 LOC107451809 sonic hedgehog protein-like aug3.g4322 hh5 -         fuchi3 -  
LOC107457189 0.00E+00 2.98533562 0.99 0.217 0.00E+00 LOC107457189 homeobox protein OTX2-A-like aug3.g9172 hh5 - ptc5 +          
LOC107444744 1.49E-295 2.47821963 0.62 0.068 3.03E-291 LOC107444744 transcription factor SOX-8 aug3.g816 hh5 -     msx6 -      
LOC107444665 5.13E-269 1.57673536 0.623 0.073 1.04E-264 LOC107444665 nuclear receptor subfamily 2 group E member 1 aug3.g794 hh5 -           fuchi5 -
LOC107452215 2.17E-170 2.07275864 0.914 0.506 4.42E-166 LOC107452215 Krueppel-like factor 7 aug3.g4601 hh5 -            
LOC107457313 2.96E-155 1.43091925 0.583 0.134 6.01E-151 LOC107457313 transcription factor Sox-2 aug3.g11061 hh5 -     msx6 -      
LOC107457180 2.30E-113 1.1754935 0.818 0.403 4.67E-109 LOC107457180 protein jagged-1 aug3.g9162,aug3.g9161 hh5 -            
LOC107436125 1.06E-96 0.71792481 0.344 0.063 2.15E-92 LOC107436125 protein gooseberry aug3.g11337 hh5 - ptc5 +         fuchi5 -
LOC107456035 3.39E-91 1.28022091 0.841 0.404 6.89E-87 LOC107456035 homeobox protein B-H1 aug3.g8250 hh5 - ptc5 +   msx6 +      
LOC107437937 2.58E-90 1.0832801 0.577 0.199 5.24E-86 LOC107437937 zinc finger protein Noc aug3.g12685,aug3.g23139 hh5 -            
LOC107449611 8.88E-82 0.97876147 0.975 0.792 1.80E-77 LOC107449611 protein dachsous aug3.g2859 hh5 -            
LOC107440157 7.07E-81 1.08988574 0.853 0.466 1.44E-76 LOC107440157 zinc finger protein 423 aug3.g14296 hh5 - ptc5 +          
LOC107448560 2.14E-74 0.50996391 0.126 0.007 4.36E-70 LOC107448560 homeobox protein EMX2 aug3.g2297              
LOC107438758 2.96E-71 0.90691936 0.992 0.878 6.02E-67 LOC107438758 epidermal growth factor receptor aug3.g13345,aug3.g13344              
LOC107445741 9.73E-65 0.61001233 0.233 0.042 1.98E-60 LOC107445741 MAM and LDL-receptor class A domain-containing protein 1 aug3.g18713,aug3.g22107              
LOC107438011 1.69E-63 0.7340836 0.524 0.202 3.44E-59 LOC107438011 neurogenic locus protein delta aug3.g12734 hh5 - ptc5 +         fuchi5 -
LOC107457564 2.49E-54 1.16494375 0.291 0.079 5.05E-50 LOC107457564 homeobox protein OTX2 aug3.g25936              
LOC107437305 5.47E-53 0.9637816 0.78 0.453 1.11E-48 LOC107437305 zinc finger protein ZIC 4-like aug3.g12202 hh5 - ptc5 +          
LOC107445428 5.44E-52 0.88939421 0.62 0.308 1.11E-47 LOC107445428 BMP and activin membrane-bound inhibitor homolog aug3.g18541              
LOC107446074 8.09E-52 0.74950132 0.956 0.85 1.64E-47 LOC107446074 glypican-5 aug3.g1222              
LOC107446521 9.52E-50 0.72073794 0.214 0.047 1.93E-45 LOC107446521 protein Wnt-11b-2 aug3.g1356              
LOC107456521 6.52E-49 0.88676737 0.872 0.659 1.33E-44 LOC107456521 ephrin-B2a aug3.g25262   ptc5 -          
LOC107456902 2.10E-45 0.63886157 0.254 0.071 4.26E-41 LOC107456902 homeobox protein dve-1 aug3.g8928,aug3.g5686 hh5 -            
LOC107455686 1.01E-44 1.02763124 0.463 0.201 2.05E-40 LOC107455686 homeobox protein Hox-A1-like aug3.g7954 hh5 - ptc5 +          
LOC107447307 5.70E-43 0.72456164 0.623 0.327 1.16E-38 LOC107447307 uncharacterized LOC107447307 aug3.g21167              
LOC107449833 1.03E-42 0.61388943 0.981 0.925 2.10E-38 LOC107449833 autism susceptibility gene 2 protein aug3.g2985,aug3.g22797,aug3.g21033 hh5 -            
LOC107451942 6.03E-42 1.00720489 0.677 0.424 1.22E-37 LOC107451942 protein NDNF aug3.g4413 hh5 - ptc5 -          
LOC122269602 1.39E-38 0.6237249 0.163 0.034 2.83E-34 LOC122269602 MDS1 and EVI1 complex locus protein EVI1-A-like aug3.g11431              
LOC107453922 7.28E-38 0.60385318 0.258 0.082 1.48E-33 LOC107453922 four-jointed box protein 1 aug3.g5891              
LOC107450518 3.16E-36 0.57446442 0.929 0.768 6.43E-32 LOC107450518 neurogenic locus Notch protein aug3.g21218           fuchi3 -  
LOC107450899 8.89E-36 0.2793548 0.883 0.582 1.81E-31 LOC107450899 sal-like protein 1 aug3.g3675   ptc5 -   msx6 -     fuchi5 -
LOC107439303 1.19E-35 0.68193436 0.719 0.482 2.41E-31 LOC107439303 hemicentin-2 aug3.g13686              
LOC107447180 8.36E-35 0.51215428 0.7 0.387 1.70E-30 LOC107447180 protein Wnt-5b-like aug3.g1632   ptc5 -          
LOC107455688 1.72E-34 0.85784411 0.424 0.203 3.50E-30 LOC107455688 uncharacterized LOC107455688 　 　 　 　 　 　 　 　
LOC107456312 1.89E-32 0.72420389 0.685 0.481 3.83E-28 LOC107456312 smoothened homolog aug3.g8490   ptc5 +          
LOC107452888 7.38E-29 0.55174688 0.935 0.823 1.50E-24 LOC107452888 uncharacterized LOC107452888 aug3.g5060 hh5 + ptc5 -          
LOC107451197 2.56E-27 0.2788673 0.109 0.022 5.21E-23 LOC107451197 homeobox protein cut-like 1 aug3.g3872 hh5 -            
LOC107453612 2.61E-25 1.07448556 0.47 0.277 5.31E-21 LOC107453612 protein Wnt-8b-like aug3.g5617   ptc5 -         fuchi5 -
LOC107450121 2.66E-25 0.85140164 0.453 0.257 5.41E-21 LOC107450121 CD9 antigen aug3.g10506              
LOC107456634 7.60E-25 0.49759855 0.912 0.846 1.54E-20 LOC107456634 RNA polymerase-associated protein CTR9 homolog aug3.g8712,aug3.g23794              
LOC107440240 9.78E-24 0.41192977 0.696 0.465 1.99E-19 LOC107440240 protein patched-like aug3.g14374 hh5 -            
LOC110283330 3.79E-22 0.43286318 0.377 0.192 7.70E-18 LOC110283330 uncharacterized LOC110283330 aug3.g21167,aug3.g11138              
LOC107444253 3.87E-22 0.38500839 0.402 0.201 7.87E-18 LOC107444253 transcription factor HES-1-A aug3.g17723   ptc5 -          
LOC107453313 4.54E-21 0.45934538 0.281 0.131 9.23E-17 LOC107453313 protein naked cuticle homolog 1 aug3.g5391 hh5 - ptc5 +          
LOC107453260 4.98E-19 0.5384722 0.258 0.121 1.01E-14 LOC107453260 homeobox protein GBX-2 aug3.g5351 hh5 -            
LOC107451464 3.33E-16 0.32749284 0.589 0.401 6.77E-12 LOC107451464 transcription factor HES-4-A-like aug3.g4026   ptc5 -          
LOC107456630 2.03E-15 0.28846936 0.18 0.076 4.13E-11 LOC107456630 intracellular protein transport protein USO1 aug3.g8711             fuchi5 -
LOC107456864 1.80E-14 0.36002776 0.914 0.825 3.66E-10 LOC107456864 exonuclease GOR-like aug3.g18504,aug3.g1256              
LOC107443537 3.03E-14 0.3241618 0.973 0.94 6.15E-10 LOC107443537 uncharacterized LOC107443537 aug3.g471              
LOC107437772 1.01E-13 0.40715402 0.82 0.706 2.05E-09 LOC107437772 MICAL-like protein 2 aug3.g12570 hh5 -            
LOC107439350 2.06E-12 0.39698808 0.524 0.387 4.19E-08 LOC107439350 protein 60A aug3.g13706   ptc5 +          
LOC107456324 6.02E-12 0.44027965 0.627 0.494 1.22E-07 LOC107456324 LIX1-like protein aug3.g8496              
LOC107451344 7.84E-12 0.39928173 0.704 0.587 1.59E-07 LOC107451344 protein c-ets-1-B aug3.g3965,aug3.g3964 hh5 -            
LOC107454132 1.05E-11 0.48943478 0.245 0.137 2.14E-07 LOC107454132 toll-like receptor Tollo aug3.g6063   ptc5 -          
LOC107436800 2.10E-11 0.40108317 0.298 0.182 4.26E-07 LOC107436800 uncharacterized LOC107436800 aug3.g11835             fuchi5 +
LOC107438242 2.25E-11 0.31322083 0.859 0.738 4.56E-07 LOC107438242 growth arrest-specific protein 2 aug3.g12936 hh5 +            
LOC107447725 4.42E-11 0.37609947 0.455 0.322 8.99E-07 LOC107447725 uncharacterized LOC107447725 aug3.g1888              
LOC107449667 8.49E-11 0.40237459 0.396 0.265 1.72E-06 LOC107449667 centromere-associated protein E aug3.g10461 hh5 - ptc5 +       fuchi3 -  
LOC107454926 1.48E-10 0.32652388 0.493 0.35 3.01E-06 LOC107454926 bcl-2-like protein 1 aug3.g23010,aug3.g6695,aug3.g6694 hh5 -            
LOC107449016 1.65E-10 0.37948441 0.306 0.188 3.36E-06 LOC107449016 uncharacterized LOC107449016 aug3.g2534,aug3.g2533              
LOC107456233 2.12E-10 0.3170799 0.954 0.928 4.30E-06 LOC107456233 amyloid-beta-like protein aug3.g8414         fuchi2 - fuchi3 -  
LOC107446561 1.71E-09 0.38015682 0.26 0.16 3.47E-05 LOC107446561 small conductance calcium-activated potassium channel protein aug3.g1380,aug3.g23104              
LOC107451348 3.19E-09 0.29439542 0.826 0.765 6.47E-05 LOC107451348 uncharacterized LOC107451348 　 　 　 　 　 　 　 　
LOC107453601 8.53E-09 0.31786997 0.746 0.653 1.73E-04 LOC107453601 protein transport protein Sec24A aug3.g5615              
LOC107439618 1.05E-08 0.25925434 0.228 0.138 2.14E-04 LOC107439618 uncharacterized LOC107439618 aug3.g13925,aug3.g11879 hh5 -            
LOC107446082 1.40E-08 0.32666042 0.491 0.37 2.85E-04 LOC107446082 sodium- and chloride-dependent glycine transporter 1 aug3.g1218              
LOC107445872 2.45E-08 0.28349841 0.887 0.824 4.99E-04 LOC107445872 uncharacterized LOC107445872 aug3.g1187              
LOC107437115 1.15E-06 0.29586068 0.755 0.655 2.35E-02 LOC107437115 one cut domain family member 2 aug3.g26177              
LOC107451441 1.41E-06 0.26714934 0.482 0.383 2.86E-02 LOC107451441 uncharacterized LOC107451441 aug3.g4013              
LOC107457517 1.88E-06 0.2517382 0.723 0.611 3.82E-02 LOC107457517 G1/S-specific cyclin-D2 aug3.g11246,aug3.g11247 hh5 - ptc5 -          
LOC107444952 1.96E-06 0.33373302 0.289 0.201 3.97E-02 LOC107444952 sterol carrier protein 2 aug3.g878 hh5 +            
LOC122271541 1.08E-05 0.25008657 0.424 0.343 2.20E-01 LOC122271541 uncharacterized LOC122271541 aug3.g14918              
LOC107446669 1.24E-05 0.27360187 0.522 0.439 2.51E-01 LOC107446669 thyroid adenoma-associated protein homolog aug3.g25636,aug3.g25637,aug3.g22198              
LOC107456664 1.46E-05 0.29944398 0.407 0.33 2.97E-01 LOC107456664 uncharacterized LOC107456664 aug3.g8740              
LOC107436783 3.23E-05 0.44035398 0.371 0.298 6.55E-01 LOC107436783 teneurin-m aug3.g11824,aug3.g22153,aug3.g11825 hh5 +           fuchi5 +