| RelatedData1.5 Cluster 4 markers identified in single-nucleus
RNA-seq analysis of P. tepidariorum embryos at late stage 5 |
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| Gene ID (NCBI) |
p_val |
avg_log2FC |
*pct.1 |
*pct.2 |
p_val_adj |
Gene ID (NCBI) |
Product (NCBI) |
aug3 gene model |
Expression in RNAi
embryos** |
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| LOC107444265 |
0.00E+00 |
2.37266809 |
0.771 |
0.081 |
0.00E+00 |
LOC107444265 |
noggin-2 |
aug3.g17729 |
hh5 - |
ptc5 - |
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fuchi3 - |
fuchi5 - |
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| LOC107448880 |
1.08E-291 |
3.71380553 |
0.961 |
0.223 |
2.19E-287 |
LOC107448880 |
endothelial
transcription factor GATA-2-like |
aug3.g20514 |
hh5 - |
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fuchi2 - |
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| LOC107450977 |
2.04E-169 |
0.87750286 |
0.329 |
0.02 |
4.15E-165 |
LOC107450977 |
T-box
transcription factor TBX3 |
aug3.g3746 |
hh5 - |
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| LOC107437748 |
2.16E-131 |
1.72897525 |
0.961 |
0.584 |
4.39E-127 |
LOC107437748 |
adipolin |
aug3.g12543 |
hh5 - |
ptc5 + |
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| LOC107443591 |
1.90E-110 |
1.87431581 |
0.917 |
0.53 |
3.86E-106 |
LOC107443591 |
BMP and activin
membrane-bound inhibitor homolog |
aug3.g17346 |
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| LOC107451864 |
5.07E-72 |
1.18751847 |
0.42 |
0.103 |
1.03E-67 |
LOC107451864 |
gonadotropin-releasing
hormone II receptor |
aug3.g4360 |
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| LOC107450980 |
2.59E-61 |
0.38484121 |
0.135 |
0.01 |
5.27E-57 |
LOC107450980 |
T-box
transcription factor TBX3-like |
aug3.g3745,aug3.g5279 |
hh5 - |
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| LOC107437564 |
8.50E-58 |
1.25195417 |
0.71 |
0.36 |
1.73E-53 |
LOC107437564 |
uncharacterized
LOC107437564 |
aug3.g12420 |
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ptc5 + |
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| LOC107440570 |
2.02E-55 |
0.92789743 |
0.638 |
0.293 |
4.10E-51 |
LOC107440570 |
uncharacterized
LOC107440570 |
aug3.g14649,aug3.g10456 |
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fuchi3 - |
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| LOC107453177 |
3.06E-42 |
0.68758119 |
0.182 |
0.032 |
6.22E-38 |
LOC107453177 |
T-box
transcription factor TBX3 |
aug3.g5279 |
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| LOC107446080 |
2.05E-41 |
0.85584069 |
0.815 |
0.506 |
4.17E-37 |
LOC107446080 |
cyclin-dependent
kinase 20 |
aug3.g1238 |
hh5 + |
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| LOC107451108 |
6.23E-38 |
0.71504721 |
0.213 |
0.048 |
1.27E-33 |
LOC107451108 |
optomotor-blind
protein |
aug3.g3790 |
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| LOC107450100 |
1.05E-36 |
0.97977032 |
0.688 |
0.373 |
2.13E-32 |
LOC107450100 |
homeobox protein
DLX-6-like |
aug3.g15531 |
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ptc5 - |
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| LOC107437772 |
6.77E-35 |
0.79247562 |
0.881 |
0.705 |
1.37E-30 |
LOC107437772 |
MICAL-like
protein 2 |
aug3.g12570 |
hh5 - |
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| LOC107447970 |
6.46E-32 |
0.58439693 |
0.975 |
0.888 |
1.31E-27 |
LOC107447970 |
aurora kinase C |
aug3.g15230 |
hh5 + |
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| LOC107452006 |
2.37E-28 |
0.79699522 |
0.702 |
0.414 |
4.82E-24 |
LOC107452006 |
transcription
factor AP-2-beta |
aug3.g23531 |
hh5 + |
ptc5 - |
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| LOC107456830 |
9.27E-27 |
0.73747819 |
0.856 |
0.655 |
1.88E-22 |
LOC107456830 |
serine-rich
adhesin for platelets |
aug3.g8856 |
hh5 - |
ptc5 + |
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| LOC122272484 |
1.28E-26 |
0.57306113 |
0.232 |
0.071 |
2.60E-22 |
LOC122272484 |
uncharacterized
LOC122272484 |
aug3.g27574 |
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| LOC107453548 |
2.28E-24 |
0.41125765 |
0.213 |
0.067 |
4.63E-20 |
LOC107453548 |
mothers against
decapentaplegic homolog 6 |
aug3.g5567 |
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| LOC107436894 |
2.96E-24 |
0.68600649 |
0.876 |
0.705 |
6.01E-20 |
LOC107436894 |
zinc finger
protein rotund |
aug3.g394 |
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| LOC107441660 |
1.08E-23 |
0.56664072 |
0.851 |
0.674 |
2.19E-19 |
LOC107441660 |
unconventional
myosin-Ie |
aug3.g9845,aug3.g9846,aug3.g22123 |
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| LOC107456104 |
1.39E-23 |
0.66692136 |
0.42 |
0.201 |
2.82E-19 |
LOC107456104 |
uncharacterized
LOC107456104 |
aug3.g10934,aug3.g18321 |
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ptc5 - |
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| LOC107454377 |
3.18E-22 |
0.69948068 |
0.776 |
0.601 |
6.46E-18 |
LOC107454377 |
bone
morphogenetic protein receptor type-2-like |
aug3.g380,aug3.g379,aug3.g22126 |
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| LOC107449611 |
1.49E-20 |
0.51124564 |
0.948 |
0.801 |
3.03E-16 |
LOC107449611 |
protein dachsous |
aug3.g2859 |
hh5 - |
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| LOC107444258 |
2.41E-20 |
0.27406175 |
0.146 |
0.039 |
4.90E-16 |
LOC107444258 |
urease subunit
alpha |
aug3.g17730 |
hh5 - |
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fuchi5 - |
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| LOC107442925 |
3.33E-20 |
0.50564555 |
0.89 |
0.731 |
6.76E-16 |
LOC107442925 |
bone
morphogenetic protein 4-like |
aug3.g16926 |
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| LOC107456960 |
3.66E-20 |
0.48646548 |
0.895 |
0.724 |
7.44E-16 |
LOC107456960 |
suppressor of
cytokine signaling 2 |
aug3.g25340,aug3.g25341 |
hh5 - |
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| LOC107436350 |
2.73E-19 |
0.4949414 |
0.95 |
0.839 |
5.56E-15 |
LOC107436350 |
glypican-6 |
aug3.g11833,aug3.g11486 |
hh5 - |
ptc5 + |
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| LOC107450335 |
1.17E-18 |
0.72897894 |
0.492 |
0.287 |
2.37E-14 |
LOC107450335 |
zinc finger
protein basonuclin-2 |
aug3.g3273 |
hh5 + |
ptc5 - |
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| LOC107437034 |
1.83E-18 |
0.61326516 |
0.58 |
0.377 |
3.72E-14 |
LOC107437034 |
Fanconi anemia
group M protein |
aug3.g26151 |
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| LOC107440453 |
2.76E-17 |
0.55753 |
0.762 |
0.593 |
5.62E-13 |
LOC107440453 |
histone
acetyltransferase KAT5 |
aug3.g14550 |
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| LOC107449282 |
6.33E-17 |
0.36882334 |
0.997 |
0.992 |
1.29E-12 |
LOC107449282 |
uncharacterized
LOC107449282 |
aug3.g20669 |
hh5 - |
ptc5 + |
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| LOC107450033 |
1.30E-16 |
0.45565911 |
0.71 |
0.514 |
2.64E-12 |
LOC107450033 |
protein
pangolin, isoforms A/H/I/S |
aug3.g10490,aug3.g18357 |
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| LOC107443364 |
1.36E-16 |
0.53501238 |
0.765 |
0.565 |
2.76E-12 |
LOC107443364 |
uncharacterized
LOC107443364 |
aug3.g17172 |
hh5 + |
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| LOC107438714 |
2.96E-16 |
0.35444582 |
0.939 |
0.78 |
6.01E-12 |
LOC107438714 |
transcriptional
activator cubitus interruptus-like |
aug3.g13321 |
hh5 + |
ptc5 - |
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| LOC107443668 |
3.44E-16 |
0.56134035 |
0.373 |
0.195 |
6.99E-12 |
LOC107443668 |
metalloprotease
TIKI2 |
aug3.g17382,aug3.g18676 |
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| LOC107451488 |
5.91E-16 |
0.65316868 |
0.693 |
0.555 |
1.20E-11 |
LOC107451488 |
ubiquitin-protein
ligase E3A |
aug3.g4064 |
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| LOC107436691 |
6.70E-16 |
0.482735 |
0.859 |
0.705 |
1.36E-11 |
LOC107436691 |
uncharacterized
LOC107436691 |
aug3.g11765 |
hh5 - |
ptc5 - |
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| LOC107455774 |
1.09E-15 |
0.64279701 |
0.461 |
0.284 |
2.21E-11 |
LOC107455774 |
patatin-like
phospholipase domain-containing protein 2 |
aug3.g8015 |
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ptc5 - |
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| LOC107437616 |
1.32E-15 |
0.4158422 |
0.948 |
0.93 |
2.69E-11 |
LOC107437616 |
nucleolar
transcription factor 1-B |
aug3.g9540 |
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| LOC107440157 |
3.23E-15 |
0.56720869 |
0.702 |
0.493 |
6.55E-11 |
LOC107440157 |
zinc finger
protein 423 |
aug3.g14296 |
hh5 - |
ptc5 + |
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| LOC107438301 |
3.33E-15 |
0.53534748 |
0.541 |
0.344 |
6.77E-11 |
LOC107438301 |
zinc finger
protein 236 |
aug3.g12961 |
hh5 + |
ptc5 - |
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| LOC107453597 |
2.41E-14 |
0.6820011 |
0.862 |
0.74 |
4.90E-10 |
LOC107453597 |
fibroblast
growth factor 8 |
aug3.g5611 |
hh5 - |
ptc5 + |
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| LOC107451348 |
4.27E-13 |
0.44680413 |
0.862 |
0.764 |
8.68E-09 |
LOC107451348 |
uncharacterized
LOC107451348 |
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| LOC107457357 |
5.17E-12 |
0.34740094 |
0.24 |
0.118 |
1.05E-07 |
LOC107457357 |
tyrosine-protein
kinase RYK |
aug3.g25882 |
hh5 - |
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| LOC107448645 |
6.31E-12 |
0.40358004 |
0.699 |
0.507 |
1.28E-07 |
LOC107448645 |
transcription
factor Sp9 |
aug3.g2333 |
hh5 - |
ptc5 - |
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| LOC107445501 |
4.55E-11 |
0.30613571 |
0.945 |
0.878 |
9.23E-07 |
LOC107445501 |
transducin-like
enhancer protein 4 |
aug3.g25605,aug3.g25606 |
hh5 - |
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| LOC107449413 |
7.68E-11 |
0.32861506 |
0.11 |
0.039 |
1.56E-06 |
LOC107449413 |
runt-related
transcription factor 1 |
aug3.g2762 |
hh5 - |
ptc5 + |
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| LOC122269063 |
1.37E-10 |
0.36957187 |
0.218 |
0.109 |
2.78E-06 |
LOC122269063 |
uncharacterized
LOC122269063 |
aug3.g11277 |
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| LOC107438828 |
2.30E-10 |
0.30413406 |
0.931 |
0.853 |
4.68E-06 |
LOC107438828 |
protein mothers
against dpp |
aug3.g26552 |
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| LOC107444058 |
3.48E-10 |
0.42947124 |
0.279 |
0.156 |
7.07E-06 |
LOC107444058 |
putative
sodium-dependent multivitamin transporter |
aug3.g7417 |
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| LOC107437559 |
3.54E-10 |
0.38040685 |
0.343 |
0.209 |
7.19E-06 |
LOC107437559 |
cytoplasmic
polyadenylation element-binding protein 1 |
aug3.g12413 |
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| LOC107456793 |
4.72E-10 |
0.55839998 |
0.202 |
0.099 |
9.60E-06 |
LOC107456793 |
T-box
transcription factor TBX20 |
aug3.g8837 |
hh5 - |
ptc5 + |
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| LOC107437743 |
6.22E-10 |
0.50147825 |
0.373 |
0.247 |
1.26E-05 |
LOC107437743 |
programmed cell
death protein 5-like |
aug3.g18027 |
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| LOC107456088 |
1.45E-09 |
0.39493675 |
0.448 |
0.302 |
2.94E-05 |
LOC107456088 |
iroquois-class
homeodomain protein IRX-6 |
aug3.g8295 |
hh5 - |
ptc5 - |
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msx6 + |
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fuchi3 + |
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| LOC107444082 |
3.45E-09 |
0.33206721 |
0.862 |
0.783 |
7.00E-05 |
LOC107444082 |
homeodomain-interacting
protein kinase 2 |
aug3.g619,aug3.g618 |
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| LOC107438587 |
2.53E-08 |
0.28888321 |
0.304 |
0.186 |
5.14E-04 |
LOC107438587 |
uncharacterized
LOC107438587 |
aug3.g13211 |
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| LOC107448644 |
4.46E-08 |
0.28491724 |
0.738 |
0.611 |
9.06E-04 |
LOC107448644 |
transcription
factor Sp4 |
aug3.g2326 |
hh5 - |
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| LOC107449016 |
2.64E-07 |
0.32887071 |
0.301 |
0.192 |
5.36E-03 |
LOC107449016 |
uncharacterized
LOC107449016 |
aug3.g2534,aug3.g2533 |
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| LOC122273004 |
2.98E-07 |
0.26751721 |
0.182 |
0.098 |
6.05E-03 |
LOC122273004 |
uncharacterized
LOC122273004 |
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| LOC107438948 |
3.02E-07 |
0.37637388 |
0.428 |
0.302 |
6.13E-03 |
LOC107438948 |
rhomboid-related
protein 2 |
aug3.g13482 |
hh5 - |
ptc5 - |
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msx6 + |
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| LOC107452884 |
2.33E-06 |
0.25577787 |
0.782 |
0.722 |
4.73E-02 |
LOC107452884 |
mitochondrial
uncoupling protein 2 |
aug3.g5048 |
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| LOC107451394 |
5.66E-06 |
0.30085058 |
0.395 |
0.283 |
1.15E-01 |
LOC107451394 |
frizzled-5 |
aug3.g4009 |
hh5 - |
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| LOC107447180 |
8.58E-06 |
0.32025973 |
0.536 |
0.413 |
1.74E-01 |
LOC107447180 |
protein
Wnt-5b-like |
aug3.g1632 |
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ptc5 - |
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| LOC107439046 |
1.05E-05 |
0.28000354 |
0.315 |
0.215 |
2.13E-01 |
LOC107439046 |
homeobox protein
extradenticle |
aug3.g13538,aug3.g27748,aug3.g27747 |
hh5 - |
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| LOC107446082 |
2.07E-05 |
0.35003266 |
0.481 |
0.376 |
4.20E-01 |
LOC107446082 |
sodium- and
chloride-dependent glycine transporter 1 |
aug3.g1218 |
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| LOC107445904 |
4.30E-05 |
0.28299803 |
0.39 |
0.294 |
8.73E-01 |
LOC107445904 |
cryptochrome-1 |
aug3.g18846 |
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| LOC107454846 |
4.86E-05 |
0.28333036 |
0.704 |
0.617 |
9.87E-01 |
LOC107454846 |
RNA-binding
protein fusilli |
aug3.g10830 |
hh5 - |
ptc5 + |
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| LOC107437003 |
9.65E-05 |
0.25660071 |
0.265 |
0.184 |
1.00E+00 |
LOC107437003 |
uncharacterized
LOC107437003 |
aug3.g11953 |
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fuchi3 - |
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| LOC107437170 |
1.88E-04 |
0.27503937 |
0.149 |
0.091 |
1.00E+00 |
LOC107437170 |
claudin
domain-containing protein 1 |
aug3.g12091 |
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| LOC107436783 |
1.93E-04 |
0.30108288 |
0.387 |
0.3 |
1.00E+00 |
LOC107436783 |
teneurin-m |
aug3.g11824,aug3.g22153,aug3.g11825 |
hh5 + |
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fuchi5 + |
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| LOC107456568 |
2.00E-04 |
0.25498756 |
0.646 |
0.579 |
1.00E+00 |
LOC107456568 |
sodium/potassium-transporting
ATPase subunit alpha |
aug3.g8662 |
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| LOC107438435 |
2.76E-04 |
0.25151726 |
0.68 |
0.605 |
1.00E+00 |
LOC107438435 |
uncharacterized
LOC107438435 |
aug3.g13086 |
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| LOC107451216 |
4.58E-04 |
0.25864891 |
0.522 |
0.438 |
1.00E+00 |
LOC107451216 |
F-box only
protein 43 |
aug3.g10565,aug3.g23000 |
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| LOC107440894 |
7.48E-04 |
0.26137391 |
0.425 |
0.341 |
1.00E+00 |
LOC107440894 |
latrophilin Cirl |
aug3.g56 |
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| LOC107456818 |
7.50E-04 |
0.27749259 |
0.417 |
0.343 |
1.00E+00 |
LOC107456818 |
gelsolin,
cytoplasmic |
aug3.g25310 |
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| LOC107440815 |
1.16E-03 |
0.25015906 |
0.417 |
0.337 |
1.00E+00 |
LOC107440815 |
uncharacterized
LOC107440815 |
aug3.g27168 |
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| LOC107448788 |
1.21E-03 |
0.269385 |
0.486 |
0.413 |
1.00E+00 |
LOC107448788 |
uncharacterized
LOC107448788 |
aug3.g2414,aug3.g2415 |
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| LOC107446084 |
2.41E-03 |
0.26468344 |
0.359 |
0.288 |
1.00E+00 |
LOC107446084 |
cordon-bleu
protein-like 1 |
aug3.g1241 |
hh5 - |
ptc5 + |
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| LOC107441035 |
2.34E-02 |
0.3096552 |
0.21 |
0.168 |
1.00E+00 |
LOC107441035 |
connectin |
aug3.g27196,aug3.g27195 |
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ptc5 - |
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fuchi5 + |
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